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CATH Superfamily 3.90.226.10

2-enoyl-CoA Hydratase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
2-enoyl-CoA Hydratase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Fatty acid oxidation complex subunit alpha

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Enoyl-CoA hydratase. [EC: 4.2.1.17]
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
  • Acts in the reverse direction.
  • With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
 1026 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1
(1016 more...)
3-hydroxybutyryl-CoA epimerase. [EC: 5.1.2.3]
(S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
    		 1016 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1
    (1006 more...)
    3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.35]
    (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
    • Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate.
    • Some enzymes act, more slowly, with NADP(+).
    • Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
    		 1016 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029HTQ0 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1 A0A029IPQ1
    (1006 more...)
    Long-chain-3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.211]
    A long-chain (S)-3-hydroxyacyl-CoA + NAD(+) = a long-chain 3-oxoacyl-CoA + NADH.
    • This enzyme was purified from the mitochondrial inner membrane.
    • The enzyme has a preference for long-chain substrates, and activity with C(16) substrates was 6- to 15-fold higher than with C(4) substrates (cf. EC 1.1.1.35).
    		 10 A0A480V8E1 A0A480V8E1 E9KL44 E9KL44 P40939 P40939 Q29554 Q29554 Q64428 Q8BMS1
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