The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 595: Phosphatase and tensin homolog A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipid phosphatase activity GO:0042577
Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
1 A0A2R8PY11 (/IDA)
Lipid phosphatase activity GO:0042577
Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
1 A0A2R8PY11 (/IMP)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
1 A0A2R8PY11 (/IMP)
Myeloid cell activation involved in immune response GO:0002275
A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
1 A0A2R8PY11 (/IGI)
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
1 A0A2R8PY11 (/IGI)
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
1 A0A2R8PY11 (/IMP)
Axon regeneration GO:0031103
The regrowth of axons following their loss or damage.
1 A0A2R8PY11 (/IMP)
Lifelong otolith mineralization GO:0031174
The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.
1 A0A2R8PY11 (/IMP)
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
1 A0A2R8PY11 (/IDA)
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
1 A0A2R8PY11 (/IMP)
Regulation of protein kinase B signaling GO:0051896
Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
1 A0A2R8PY11 (/IMP)
Myeloid cell development GO:0061515
The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.
1 A0A2R8PY11 (/IGI)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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