The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Protein tyrosine phosphatase superfamily
".
FunFam 57: Dual specificity phosphatase 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | Q16690 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q16690 (/IPI) |
|
Protein tyrosine/serine/threonine phosphatase activity GO:0008138
Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | Q16690 (/IDA) |
|
Protein tyrosine/serine/threonine phosphatase activity GO:0008138
Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
|
1 | Q1HL35 (/ISO) |
|
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
1 | Q16690 (/IDA) |
|
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
1 | Q1HL35 (/ISO) |
|
MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017
Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.
|
1 | O54838 (/IDA) |
|
MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017
Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.
|
1 | Q1HL35 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
1 | Q16690 (/TAS) |
|
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
|
1 | Q16690 (/TAS) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q16690 (/TAS) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
1 | Q16690 (/IDA) |
|
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
1 | Q1HL35 (/ISO) |
|
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
|
1 | Q16690 (/IDA) |
|
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
|
1 | Q1HL35 (/ISO) |
|
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
|
1 | O54838 (/ISS) |
|
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
|
1 | Q16690 (/IDA) |
|
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
|
1 | Q1HL35 (/ISO) |
|
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
|
1 | O54838 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | O54838 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q1HL35 (/ISO) |
|
Negative regulation of vasoconstriction GO:0045906
Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.
|
1 | O54838 (/IMP) |
|
Negative regulation of vasoconstriction GO:0045906
Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.
|
1 | Q1HL35 (/ISO) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q16690 (/TAS) |
