The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 45: Tyrosine-protein phosphatase non-receptor type 12

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 22 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O82656 (/IPI) P29352 (/IPI) P35831 (/IPI) P70602 (/IPI) Q05209 (/IPI) Q61152 (/IPI) Q99952 (/IPI) Q9Y2R2 (/IPI)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
4 G3V7Q4 (/IDA) O82656 (/IDA) Q63745 (/IDA) Q9Y2R2 (/IDA)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
3 P29352 (/ISO) P35831 (/ISO) Q61152 (/ISO)
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
2 P35831 (/IDA) Q05209 (/IDA)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
2 Q05209 (/EXP) Q99952 (/EXP)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
2 D4A2D5 (/ISS) P29352 (/ISS)
Non-membrane spanning protein tyrosine phosphatase activity GO:0004726
Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.
2 Q05209 (/TAS) Q99952 (/TAS)
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
2 P29352 (/IPI) Q05209 (/IPI)
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
2 D4A2D5 (/ISS) Q9Y2R2 (/ISS)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
2 O82656 (/IPI) P29352 (/IPI)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
2 D4A2D5 (/ISS) Q9Y2R2 (/ISS)
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
1 P35831 (/ISO)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
1 Q9Y2R2 (/TAS)
Non-membrane spanning protein tyrosine phosphatase activity GO:0004726
Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.
1 Q61152 (/IDA)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
1 Q9Y2R2 (/IDA)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
1 P29352 (/ISO)
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
1 P35831 (/ISO)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 Q9Y2R2 (/IPI)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 P29352 (/ISO)
MAP kinase tyrosine phosphatase activity GO:0033550
Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.
1 O82656 (/IDA)
Protein tyrosine kinase binding GO:1990782
Interacting selectively and non-covalently with protein tyrosine kinase.
1 D4A2D5 (/IPI)
Protein tyrosine kinase binding GO:1990782
Interacting selectively and non-covalently with protein tyrosine kinase.
1 P29352 (/ISO)

There are 90 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
3 P35831 (/IDA) Q05209 (/IDA) Q9Y2R2 (/IDA)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
3 Q05209 (/TAS) Q99952 (/TAS) Q9Y2R2 (/TAS)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
2 P29352 (/ISO) P35831 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Regulation of natural killer cell proliferation GO:0032817
Any process that modulates the frequency, rate or extent of natural killer cell proliferation.
2 D4A2D5 (/ISS) P29352 (/ISS)
Positive regulation of toll-like receptor 3 signaling pathway GO:0034141
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Phosphoanandamide dephosphorylation GO:0035644
The process of removing one or more phosphate groups from a phosphorylated anandamide.
2 D4A2D5 (/ISS) Q9Y2R2 (/ISS)
ERBB2 signaling pathway GO:0038128
A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.
2 Q05209 (/TAS) Q99952 (/TAS)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
2 G3V7Q4 (/IEP) Q63745 (/IEP)
Negative regulation of T cell activation GO:0050868
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0070433
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Cellular response to muramyl dipeptide GO:0071225
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
2 P29352 (/IDA) Q9Y2R2 (/IDA)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 Q05209 (/TAS) Q99952 (/TAS)
Negative regulation of interleukin-6 secretion GO:1900165
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of ERBB signaling pathway GO:1901185
Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.
2 Q05209 (/TAS) Q99952 (/TAS)
Regulation of NIK/NF-kappaB signaling GO:1901222
Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Positive regulation of protein K63-linked ubiquitination GO:1902523
Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of p38MAPK cascade GO:1903753
Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Negative regulation of interleukin-8 secretion GO:2000483
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-8 secretion.
2 P29352 (/IMP) Q9Y2R2 (/IMP)
Blastocyst formation GO:0001825
The initial formation of a blastocyst from a solid ball of cells known as a morula.
1 Q61152 (/IMP)
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
1 P29352 (/IMP)
Regulation of leukocyte migration GO:0002685
Any process that modulates the frequency, rate, or extent of leukocyte migration.
1 P29352 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 P29352 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 D4A2D5 (/ISS)
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 Q9Y2R2 (/IMP)
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 P29352 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P29352 (/ISO)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P29352 (/ISO)
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
1 P29352 (/IMP)
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
1 Q9Y2R2 (/ISS)
Negative regulation of defense response GO:0031348
Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
1 O82656 (/IGI)
Lipopolysaccharide-mediated signaling pathway GO:0031663
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 Q9Y2R2 (/IMP)
Lipopolysaccharide-mediated signaling pathway GO:0031663
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1 P29352 (/ISO)
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 Q9Y2R2 (/IMP)
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 P29352 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q9Y2R2 (/IMP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P29352 (/ISO)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
1 P29352 (/ISO)
Regulation of natural killer cell proliferation GO:0032817
Any process that modulates the frequency, rate or extent of natural killer cell proliferation.
1 Q9Y2R2 (/IDA)
Regulation of natural killer cell proliferation GO:0032817
Any process that modulates the frequency, rate or extent of natural killer cell proliferation.
1 P29352 (/ISO)
Positive regulation of toll-like receptor 3 signaling pathway GO:0034141
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
1 P29352 (/ISO)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
1 P29352 (/ISO)
Positive regulation of toll-like receptor 7 signaling pathway GO:0034157
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
1 P29352 (/IMP)
Positive regulation of toll-like receptor 9 signaling pathway GO:0034165
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
1 P29352 (/IMP)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
1 Q05209 (/IDA)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
1 P35831 (/ISO)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
1 P35831 (/ISS)
Positive regulation of interferon-beta secretion GO:0035549
Any process that activates or increases the frequency, rate, or extent of interferon-beta secretion.
1 P29352 (/IMP)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 O82656 (/TAS)
Phosphoanandamide dephosphorylation GO:0035644
The process of removing one or more phosphate groups from a phosphorylated anandamide.
1 P29352 (/IDA)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q05209 (/IMP)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 P35831 (/ISO)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 P35831 (/ISS)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 P29352 (/IMP)
Negative regulation of JUN kinase activity GO:0043508
Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
1 Q9Y2R2 (/IMP)
Negative regulation of JUN kinase activity GO:0043508
Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
1 P29352 (/ISO)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q9Y2R2 (/IC)
Regulation of peptidyl-tyrosine phosphorylation GO:0050730
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 D4A2D5 (/IMP)
Regulation of peptidyl-tyrosine phosphorylation GO:0050730
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 P29352 (/ISO)
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
1 P29352 (/IMP)
T cell receptor signaling pathway GO:0050852
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
1 Q9Y2R2 (/TAS)
Regulation of B cell receptor signaling pathway GO:0050855
Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
1 Q9Y2R2 (/NAS)
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 Q9Y2R2 (/IDA)
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 P29352 (/ISO)
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 P29352 (/ISS)
Negative regulation of T cell activation GO:0050868
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
1 P29352 (/ISO)
Negative regulation of T cell activation GO:0050868
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
1 D4A2D5 (/ISS)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 P29352 (/ISO)
Negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0070433
Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
1 P29352 (/ISO)
Cellular response to muramyl dipeptide GO:0071225
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
1 P29352 (/ISO)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 Q05209 (/IMP)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 P35831 (/ISO)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 P35831 (/ISS)
Positive regulation of granzyme B production GO:0071663
Any process that activates or increases the frequency, rate, or extent of production of granzyme B.
1 P29352 (/IMP)
Negative regulation of interleukin-6 secretion GO:1900165
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion.
1 P29352 (/ISO)
Regulation of NIK/NF-kappaB signaling GO:1901222
Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.
1 P29352 (/ISO)
Positive regulation of protein K63-linked ubiquitination GO:1902523
Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.
1 P29352 (/ISO)
Positive regulation of interferon-gamma secretion GO:1902715
Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.
1 Q9Y2R2 (/IMP)
Positive regulation of interferon-gamma secretion GO:1902715
Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.
1 P29352 (/ISO)
Positive regulation of interferon-alpha secretion GO:1902741
Any process that activates or increases the frequency, rate or extent of interferon-alpha secretion.
1 P29352 (/IMP)
Regulation of calcium ion transmembrane transport GO:1903169
Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.
1 D4A2D5 (/IMP)
Regulation of calcium ion transmembrane transport GO:1903169
Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.
1 P29352 (/ISO)
Negative regulation of p38MAPK cascade GO:1903753
Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.
1 P29352 (/ISO)
Negative regulation of interleukin-8 secretion GO:2000483
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-8 secretion.
1 P29352 (/ISO)
Positive regulation of CD8-positive, alpha-beta T cell proliferation GO:2000566
Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
1 P29352 (/IMP)
Negative regulation of platelet-derived growth factor receptor-beta signaling pathway GO:2000587
Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
1 Q05209 (/TAS)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 D4A2D5 (/IDA) O82656 (/IDA) P29352 (/IDA) Q61152 (/IDA) Q9Y2R2 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O82656 (/IDA) P29352 (/IDA) Q61152 (/IDA) Q9Y2R2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q05209 (/TAS) Q99952 (/TAS) Q9Y2R2 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q05209 (/TAS) Q99952 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q05209 (/TAS) Q9Y2R2 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 G3V7Q4 (/NAS) Q63745 (/NAS)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
2 P29352 (/IDA) Q9Y2R2 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 D4A2D5 (/ISS) P29352 (/ISS)
Podosome GO:0002102
An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
1 P35831 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P29352 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P29352 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 D4A2D5 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P35831 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O82656 (/IDA)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P29352 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q9Y2R2 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 P29352 (/ISO)
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