The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 108: Tyrosine-protein phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
5 Q86PA5 (/IDA) Q8IRJ0 (/IDA) Q8WSF2 (/IDA) Q9NHZ3 (/IDA) Q9W0R3 (/IDA)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
4 Q86PA5 (/ISS) Q8IRJ0 (/ISS) Q8WSF2 (/ISS) Q9NHZ3 (/ISS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
5 Q86PA5 (/IMP) Q8IRJ0 (/IMP) Q8WSF2 (/IMP) Q9NHZ3 (/IMP) Q9W0R3 (/IMP)
Thermosensory behavior GO:0040040
Behavior that is dependent upon the sensation of temperature.
5 Q86PA5 (/IMP) Q8IRJ0 (/IMP) Q8WSF2 (/IMP) Q9NHZ3 (/IMP) Q9W0R3 (/IMP)
Central complex development GO:0048036
The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.
5 Q86PA5 (/IMP) Q8IRJ0 (/IMP) Q8WSF2 (/IMP) Q9NHZ3 (/IMP) Q9W0R3 (/IMP)
Axon extension involved in axon guidance GO:0048846
The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
5 Q86PA5 (/IMP) Q8IRJ0 (/IMP) Q8WSF2 (/IMP) Q9NHZ3 (/IMP) Q9W0R3 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
4 Q86PA5 (/ISS) Q8IRJ0 (/ISS) Q8WSF2 (/ISS) Q9NHZ3 (/ISS)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
4 Q86PA5 (/IDA) Q8IRJ0 (/IDA) Q8WSF2 (/IDA) Q9NHZ3 (/IDA)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
1 Q9W0R3 (/IDA)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q9W0R3 (/IGI)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q9W0R3 (/IMP)
Negative regulation of border follicle cell migration GO:1903687
Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.
1 Q9W0R3 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q86PA5 (/ISS) Q8IRJ0 (/ISS) Q8WSF2 (/ISS) Q9NHZ3 (/ISS) Q9W0R3 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 Q86PA5 (/ISS) Q8IRJ0 (/ISS) Q8WSF2 (/ISS) Q9NHZ3 (/ISS) Q9W0R3 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q86PA5 (/HDA) Q8IRJ0 (/HDA) Q8WSF2 (/HDA) Q9NHZ3 (/HDA) Q9W0R3 (/HDA)
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