The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Quinone oxidoreductase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADPH:quinone reductase activity GO:0003960
Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
8 Q48QH7 (/ISS) Q48QH7 (/ISS) Q48QH7 (/ISS) Q48QH7 (/ISS) Q48QH7 (/ISS) Q48QH7 (/ISS) Q88B47 (/ISS) Q88B47 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P28304 (/IPI) P28304 (/IPI) P28304 (/IPI) P28304 (/IPI) P28304 (/IPI) P28304 (/IPI) P28304 (/IPI) P28304 (/IPI)
NADPH:quinone reductase activity GO:0003960
Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
2 P38230 (/IDA) P38230 (/IDA)
2-alkenal reductase [NAD(P)] activity GO:0032440
Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.
2 P38230 (/IDA) P38230 (/IDA)
MRNA 3'-UTR AU-rich region binding GO:0035925
Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
2 P38230 (/IDA) P38230 (/IDA)
NADPH:quinone reductase activity GO:0003960
Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
1 O74489 (/ISO)
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
1 Q5LX26 (/ISS)
AU-rich element binding GO:0017091
Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
1 O74489 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P38230 (/IMP) P38230 (/IMP)
Response to high light intensity GO:0009644
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
1 A1L4Y4 (/IEP)
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
1 O74489 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA)
(1 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA) O53146 (/HDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 A1L4Y4 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA) P28304 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 O74489 (/HDA) P38230 (/HDA) P38230 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P38230 (/HDA) P38230 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O74489 (/HDA)
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