The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: probable cinnamyl alcohol dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cinnamyl-alcohol dehydrogenase. [EC: 1.1.1.195]
Cinnamyl alcohol + NADP(+) = cinnamaldehyde + NADPH.
  • Acts on coniferyl alcohol, sinapyl alcohol, 4-coumaryl alcohol and cinnamyl alcohol (cf. EC 1.1.1.194).
131 A0A0D9YNH0 A0A0D9YNH0 A0A0D9YNH0 A0A0D9YNH0 A0A0D9YNH0 A0A0E0G2Z8 A0A0E0G2Z8 A0A0E0G2Z8 A0A0E0G2Z8 A0A0E0G2Z8
(121 more...)
Alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.2]
An alcohol + NADP(+) = an aldehyde + NADPH.
  • Some members of this group oxidize only primary alcohols; others act also on secondary alcohols.
  • May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55.
  • Re-specific with respect to NADPH.
90 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A045GQW4 A0A0H3LDE3
(80 more...)
Geissoschizine dehydrogenase. [EC: 1.3.1.36]
Geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH.
  • Involved in the interconversion of heteroyohimbine alkaloids in Catharanthus roseus.
1 W8JWW7