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CATH Superfamily 3.90.176.10

Toxin ADP-ribosyltransferase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Toxin ADP-ribosyltransferase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: ADP-ribosyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(+)--protein-arginine ADP-ribosyltransferase. [EC: 2.4.2.31]
NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)- protein-L-arginine.
  • Arginine residues in proteins act as acceptors.
  • Free arginine, agmatine ((4-aminobutyl)guanidine), arginine methyl ester and guanidine can also do so.
  • The enzyme from some, but not all, species can also use NADP(+) as acceptor (giving rise to N(omega)-((2'-phospho-ADP)-D-ribosyl)- protein-L-arginine as the product), but more slowly.
  • Catalyzes the NAD(+)-dependent activation of EC 4.6.1.1.
  • Some bacterial enterotoxins possess similar enzymatic activities (cf. EC 2.4.2.36).
 16 A0A023ZVA6 A0A023ZVA6 A0A023ZVA6 A0A023ZVA6 A0A097J7F5 A0A097J7F5 A0A097J7F5 A0A097J7F5 A0A097J882 A0A097J882
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