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CATH Superfamily 3.90.1720.10

endopeptidase domain like (from Nostoc punctiforme)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
endopeptidase domain like (from Nostoc punctiforme)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Lecithin retinol acyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphatidylcholine--retinol O-acyltransferase. [EC: 2.3.1.135]
Phosphatidylcholine + retinol--[cellular-retinol-binding-protein] = 2-acylglycerophosphocholine + retinyl-ester--[cellular-retinol-binding- protein].
  • A key enzyme in retinoid metabolism, catalyzing the transfer of an acyl group from the sn-1 position of phosphatidylcholine to retinol, forming retinyl esters which are then stored.
  • Recognizes the substrate both in free form and when bound to cellular-retinol-binding-protein, but has higher affinity for the bound form.
  • Can also esterify 11-cis-retinol.
 22 A0A2J8MUT5 A0A2J8MUT5 A0A2J8MUT5 A0A2J8MUT5 A0A2R9CHM5 A0A2R9CHM5 A0A2R9CHM5 A0A2R9CHM5 B2RUR5 B2RUR5
(12 more...)
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