The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
H-NOX domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Soluble guanylate cyclase gcy-36

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxygen sensor activity GO:0019826
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
2 O02298 (/IMP) Q6DNF4 (/IMP)
Guanylate cyclase activity GO:0004383
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
1 Q6DNF4 (/ISS)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
1 O02298 (/IDA)
Carbon monoxide binding GO:0070025
Interacting selectively and non-covalently with carbon monoxide (CO).
1 O02298 (/IDA)
Nitric oxide binding GO:0070026
Interacting selectively and non-covalently with nitric oxide (NO).
1 O02298 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxygen levels GO:0070482
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
2 O02298 (/IMP) Q6DNF4 (/IMP)
Feeding behavior GO:0007631
Behavior associated with the intake of food.
1 Q6DNF4 (/IGI)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 P92006 (/IGI)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 P92006 (/IMP)
Aerotaxis GO:0009454
The directed movement of a motile cell or organism in response to environmental oxygen.
1 O02298 (/IMP)
CGMP-mediated signaling GO:0019934
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
1 O02298 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 O02298 (/IGI)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 P92006 (/IGI)
Sensory perception of bitter taste GO:0050913
The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 P92006 (/IMP)
Response to hyperoxia GO:0055093
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
1 O02298 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 O02298 (/IDA) Q6DNF4 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 O02298 (/IDA) Q6DNF4 (/IDA)