The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"set domain protein methyltransferase, domain 1
".
FunFam 13: N-lysine methyltransferase SETD6
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
6 | A4QNG5 (/ISS) C0H8I2 (/ISS) C0H8I2 (/ISS) Q5ZK17 (/ISS) Q6INM2 (/ISS) Q803K4 (/ISS) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Peptidyl-lysine monomethylation GO:0018026
The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
|
6 | A4QNG5 (/ISS) C0H8I2 (/ISS) C0H8I2 (/ISS) Q5ZK17 (/ISS) Q6INM2 (/ISS) Q803K4 (/ISS) |
|
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
|
6 | A4QNG5 (/ISS) C0H8I2 (/ISS) C0H8I2 (/ISS) Q5ZK17 (/ISS) Q6INM2 (/ISS) Q803K4 (/ISS) |
|
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
|
6 | A4QNG5 (/ISS) C0H8I2 (/ISS) C0H8I2 (/ISS) Q5ZK17 (/ISS) Q6INM2 (/ISS) Q803K4 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | A4QNG5 (/ISS) C0H8I2 (/ISS) C0H8I2 (/ISS) Q5ZK17 (/ISS) Q6INM2 (/ISS) Q803K4 (/ISS) |
