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CATH Superfamily 3.90.1240.10

Metalloproteases ("zincins"), catalytic domain like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Metalloproteases ("zincins"), catalytic domain like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Botulinum neurotoxin type C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)
Ganglioside binding GO:0035594
Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)
Toxin activity GO:0090729
Interacting selectively with one or more biological molecules in another organism (the \target\ organism), initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)
Negative regulation of calcium ion-dependent exocytosis GO:0045955
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
 3 P18640 (/IDA) P18640 (/IDA) P18640 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.