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CATH Superfamily 3.90.1170.50

Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Carbon monoxide dehydrogenase large chain

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glyceraldehyde dehydrogenase (FAD-containing). [EC: 1.2.99.8]
D-glyceraldehyde + H(2)O + acceptor = D-glycerate + reduced acceptor.
  • The enzyme from the archaeon Sulfolobus acidocaldarius catalyzes the oxidation of D-glyceraldehyde in the nonphosphorylative Entner- Doudoroff pathway.
  • With 2,6-dichlorophenolindophenol as artificial electron acceptor, the enzyme shows a broad substrate range, but is most active with D-glyceraldehyde.
  • It is not known which acceptor is utilized in vivo.
 16 A0A0U2VXA4 A0A0U2VXA4 A0A0U2VXA4 A0A0U2VXA4 M1J1L1 M1J1L1 M1J1L1 M1J1L1 M1J8N8 M1J8N8
(6 more...)
Caffeine dehydrogenase. [EC: 1.17.5.2]
Caffeine + ubiquinone + H(2)O = 1,3,7-trimethylurate + ubiquinol.
  • This enzyme, characterized from the soil bacterium Pseudomonas sp. CBB1, catalyzes the incorporation of an oxygen atom originating from a water molecule into position C-8 of caffeine.
  • The enzyme utilizes short-tail ubiquinones as the preferred electron acceptor.
 1 D7REY3
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