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CATH Superfamily 3.90.1170.30

Pyrimidine nucleoside phosphorylase-like, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pyrimidine nucleoside phosphorylase-like, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: AMP phosphorylase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
AMP phosphorylase. [EC: 2.4.2.57]
(1) AMP + phosphate = adenine + alpha-D-ribose 1,5-bisphosphate. (2) CMP + phosphate = cytosine + alpha-D-ribose 1,5-bisphosphate. (3) UMP + phosphate = uracil + alpha-D-ribose 1,5-bisphosphate.
  • The enzyme from archaea is involved in AMP metabolism and CO(2) fixation through type III RubisCO enzymes.
  • The activity with CMP and UMP requires activation by cAMP.
 6 B6YWT7 C5A1L9 Q58081 Q5JCX3 Q8Q0P9 Q8TL01
Thymidine phosphorylase. [EC: 2.4.2.4]
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
  • In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.
  • Formerly EC 2.4.2.23.
 4 A0A2A6N8N9 A0A2A6N8N9 Q89QK7 Q89QK7