The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 83: O-acetylhomoserine sulfhydrylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
7 O13326 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA)
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
6 P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS)
Cysteine synthase activity GO:0004124
Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
6 P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA) P06106 (/IDA)
Carbon-oxygen lyase activity GO:0016835
Catalysis of the breakage of a carbon-oxygen bond.
4 Q74AF1 (/ISS) Q74AF1 (/ISS) Q74DY2 (/ISS) Q74DY2 (/ISS)
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
2 Q6FVR1 (/IMP) Q6FVR1 (/IMP)
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
2 Q6FVR1 (/ISO) Q6FVR1 (/ISO)
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
1 O13326 (/IGI)
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
1 P50125 (/RCA)
Cysteine synthase activity GO:0004124
Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
1 O13326 (/IGI)
Cysteine synthase activity GO:0004124
Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
1 O13326 (/IMP)
Cysteine synthase activity GO:0004124
Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
1 P50125 (/RCA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
6 P06106 (/IMP) P06106 (/IMP) P06106 (/IMP) P06106 (/IMP) P06106 (/IMP) P06106 (/IMP)
Cysteine biosynthetic process GO:0019344
The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
6 P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS) P06106 (/TAS)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
4 Q74AF1 (/ISS) Q74AF1 (/ISS) Q74DY2 (/ISS) Q74DY2 (/ISS)
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
1 P50125 (/IMP)
Cysteine biosynthetic process from serine GO:0006535
The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.
1 O13326 (/IMP)
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
1 O13326 (/NAS)
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
1 P50125 (/RCA)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
1 Q59US5 (/IMP)
L-homocysteine biosynthetic process GO:0071269
The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.
1 O13326 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA) P06106 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O13326 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13326 (/HDA)
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
1 Q59US5 (/IDA)
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