The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aspartate Aminotransferase, domain 1
".
FunFam 3: Serine hydroxymethyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glycine hydroxymethyltransferase activity GO:0004372
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
|
126 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(116 more) |
|
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
|
126 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(116 more) |
|
Glycine hydroxymethyltransferase activity GO:0004372
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
|
121 |
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
(111 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
121 |
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
(111 more) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
121 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(111 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
121 |
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
P0A825 (/IPI)
(111 more) |
|
Glycine hydroxymethyltransferase activity GO:0004372
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
|
11 |
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
(1 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | P9WGI7 (/IPI) P9WGI7 (/IPI) P9WGI7 (/IPI) P9WGI7 (/IPI) P9WGI9 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glycine catabolic process GO:0006546
The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
|
121 |
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
(111 more) |
|
L-serine catabolic process GO:0006565
The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
|
121 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(111 more) |
|
Glycine biosynthetic process from serine GO:0019264
The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.
|
121 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(111 more) |
|
Glycine biosynthetic process from serine GO:0019264
The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.
|
121 |
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
P0A825 (/IMP)
(111 more) |
|
Glycine biosynthetic process GO:0006545
The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
|
11 |
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
(1 more) |
|
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
|
11 |
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KMP4 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
Q9KTG1 (/ISS)
(1 more) |
|
Glycine metabolic process GO:0006544
The chemical reactions and pathways involving glycine, aminoethanoic acid.
|
5 | P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI9 (/IDA) |
|
L-serine metabolic process GO:0006563
The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
|
5 | P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI7 (/IDA) P9WGI9 (/IDA) |
|
Active evasion of host immune response GO:0042783
Any mechanism of immune avoidance that directly affects the host immune system, e.g. blocking any stage in host MHC class I and II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | P9WGI9 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
121 |
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
(111 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
121 |
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
P0A825 (/IDA)
(111 more) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
121 |
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
P0A825 (/HDA)
(111 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | P9WGI7 (/HDA) P9WGI7 (/HDA) P9WGI7 (/HDA) P9WGI7 (/HDA) P9WGI9 (/HDA) |
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
1 | P9WGI9 (/HDA) |
