The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aspartate Aminotransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 162: Serine hydroxymethyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glycine hydroxymethyltransferase. [EC: 2.1.2.1]
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.
  • Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine.
15 A0A1Y3DZI8 A0A1Y3DZI8 A0A1Y3DZI8 A0A2J9KKI5 A0A2J9KKI5 A0A2J9KKI5 B2US14 B5Z9V7 B6JPT2 P56089
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