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CATH Superfamily 3.90.100.10

Orn/Lys/Arg decarboxylase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Orn/Lys/Arg decarboxylase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Lysine decarboxylase, inducible

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 131 P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI)
(121 more)
Lysine decarboxylase activity GO:0008923
Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).
 131 P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA)
(121 more)
Lysine decarboxylase activity GO:0008923
Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).
 73 P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP)
(63 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 73 P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI) P0A9H3 (/IPI)
(63 more)
Guanosine tetraphosphate binding GO:0097216
Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
 73 P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA) P0A9H3 (/IDA)
(63 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 58 P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA)
(48 more)
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
 20 P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA)
(10 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
 20 P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA)
(10 more)
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
 8 Q8EJZ2 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS)
Lysine decarboxylase activity GO:0008923
Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).
 4 Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysine catabolic process GO:0006554
The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.
 73 P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP) P0A9H3 (/IMP)
(63 more)
Lysine catabolic process GO:0006554
The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.
 58 P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA) P52095 (/IDA)
(48 more)
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
 18 P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP) P21169 (/IMP)
(8 more)
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
 7 Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS) Q9KKN9 (/ISS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
 4 Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
 4 Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS) Q9KV75 (/ISS)
Polyamine biosynthetic process GO:0006596
The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
 1 Q8EJZ2 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 18 P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA) P21169 (/IDA)
(8 more)