The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
tm_1862 like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Coproporphyrinogen-III oxidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
7 O25376 (/ISS) O25376 (/ISS) O25376 (/ISS) O34162 (/ISS) O67886 (/ISS) Q9ZLH0 (/ISS) Q9ZLH0 (/ISS)
Coproporphyrinogen dehydrogenase activity GO:0051989
Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
6 O25376 (/ISS) O25376 (/ISS) O25376 (/ISS) O67886 (/ISS) Q9ZLH0 (/ISS) Q9ZLH0 (/ISS)
Coproporphyrinogen oxidase activity GO:0004109
Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX.
5 Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
3 P73245 (/IDA) P74132 (/IDA) P74132 (/IDA)
Coproporphyrinogen dehydrogenase activity GO:0051989
Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
2 P74132 (/IDA) P74132 (/IDA)
Coproporphyrinogen dehydrogenase activity GO:0051989
Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
1 O34162 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Porphyrin-containing compound biosynthetic process GO:0006779
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
11 O25376 (/ISS) O25376 (/ISS) O25376 (/ISS) O67886 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9KVM5 (/ISS) Q9ZLH0 (/ISS)
(1 more)
Protoporphyrinogen IX biosynthetic process GO:0006782
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
6 O25376 (/ISS) O25376 (/ISS) O25376 (/ISS) O67886 (/ISS) Q9ZLH0 (/ISS) Q9ZLH0 (/ISS)
Porphyrin-containing compound biosynthetic process GO:0006779
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
4 O34162 (/IMP) P73245 (/IMP) P74132 (/IMP) P74132 (/IMP)
Protoporphyrinogen IX biosynthetic process GO:0006782
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
2 P74132 (/IDA) P74132 (/IDA)
Protoporphyrinogen IX biosynthetic process GO:0006782
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
1 O34162 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 O25376 (/ISS) O25376 (/ISS) O25376 (/ISS) O34162 (/ISS) O67886 (/ISS) P73245 (/ISS) P74132 (/ISS) P74132 (/ISS) Q9ZLH0 (/ISS) Q9ZLH0 (/ISS)
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