The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Inhibitor
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: Leucine rich repeats and immunoglobulin like domai...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q52KR2 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q52KR2 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
2 P70193 (/IMP) Q52KR2 (/IMP)
Otolith morphogenesis GO:0032474
The process in which the anatomical structures of an otolith are generated and organized.
2 P70193 (/IGI) Q6P1C6 (/IGI)
Innervation GO:0060384
The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
2 P70193 (/IGI) Q52KR2 (/IGI)
Regulation of platelet-derived growth factor receptor signaling pathway GO:0010640
Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
1 Q52KR2 (/IGI)
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q52KR2 (/IGI)
Hair cycle process GO:0022405
A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
1 P70193 (/IMP)
Regulation of axon regeneration GO:0048679
Any process that modulates the frequency, rate or extent of axon regeneration.
1 Q52KR2 (/IGI)
Negative regulation of axon regeneration GO:0048681
Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
1 Q52KR2 (/IMP)
Negative regulation of membrane protein ectodomain proteolysis GO:0051045
Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.
1 Q52KR2 (/IMP)
Positive regulation of protein localization to cell surface GO:2000010
Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.
1 Q52KR2 (/IMP)
Regulation of neuron migration GO:2001222
Any process that modulates the frequency, rate or extent of neuron migration.
1 Q52KR2 (/IGI)
Regulation of neuron migration GO:2001222
Any process that modulates the frequency, rate or extent of neuron migration.
1 Q52KR2 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q6UXM1 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q96JA1 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q52KR2 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
1 Q52KR2 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q52KR2 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q52KR2 (/IDA)
Intracellular vesicle GO:0097708
Any vesicle that is part of the intracellular region.
1 Q52KR2 (/IDA)
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