The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
L-arginine/glycine Amidinotransferase; Chain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Glycine amidinotransferase, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine amidinotransferase activity GO:0015068
Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.
13 P50441 (/ISS) P50441 (/ISS) P50442 (/ISS) Q2HJ74 (/ISS) Q4R806 (/ISS) Q5RFB9 (/ISS) Q5RFB9 (/ISS) Q6IU05 (/ISS) Q6P832 (/ISS) Q6PH19 (/ISS)
(3 more)
Glycine amidinotransferase activity GO:0015068
Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.
2 P50440 (/IDA) P50440 (/IDA)
Amidinotransferase activity GO:0015067
Catalysis of the reversible transfer of an amidino group to an acceptor.
1 P50442 (/IDA)
Amidinotransferase activity GO:0015067
Catalysis of the reversible transfer of an amidino group to an acceptor.
1 Q9D964 (/ISO)
Glycine amidinotransferase activity GO:0015068
Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.
1 Q9D964 (/ISO)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
4 A0A140TA89 (/ISS) P50440 (/ISS) P50440 (/ISS) P50442 (/ISS)
Creatine metabolic process GO:0006600
The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
2 P50440 (/IMP) P50440 (/IMP)
Creatine metabolic process GO:0006600
The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
2 P50440 (/TAS) P50440 (/TAS)
Creatine biosynthetic process GO:0006601
The chemical reactions and pathways resulting in the formation of creatine, N-
2 P50440 (/IDA) P50440 (/IDA)
Creatine biosynthetic process GO:0006601
The chemical reactions and pathways resulting in the formation of creatine, N-
2 Q2HJ74 (/ISS) Q6IU05 (/ISS)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2 P50440 (/IMP) P50440 (/IMP)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
2 P50440 (/IMP) P50440 (/IMP)
Muscle atrophy GO:0014889
A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
2 P50440 (/IMP) P50440 (/IMP)
Creatine metabolic process GO:0006600
The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
1 Q9D964 (/ISO)
Creatine biosynthetic process GO:0006601
The chemical reactions and pathways resulting in the formation of creatine, N-
1 Q9D964 (/ISO)
Creatine biosynthetic process GO:0006601
The chemical reactions and pathways resulting in the formation of creatine, N-
1 P50442 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P50442 (/IEP)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
1 Q9D964 (/ISO)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 P50442 (/IDA)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 Q9D964 (/ISO)
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
1 Q9D964 (/ISO)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P50442 (/IDA)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 Q9D964 (/ISO)
Muscle atrophy GO:0014889
A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
1 Q9D964 (/ISO)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
1 P50442 (/IEP)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P50442 (/IDA)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 Q9D964 (/ISO)
Response to mercury ion GO:0046689
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
1 P50442 (/IDA)
Response to mercury ion GO:0046689
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
1 Q9D964 (/ISO)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
1 Q9D964 (/IMP)
Embryonic liver development GO:1990402
The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.
1 P50442 (/IEP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 A0A140VK19 (/IDA) A0A140VK19 (/IDA) P50440 (/IDA) P50440 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q2HJ74 (/ISS) Q6IU05 (/ISS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
2 P50440 (/IDA) P50440 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
2 Q2HJ74 (/ISS) Q6IU05 (/ISS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
2 P50440 (/TAS) P50440 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P50440 (/HDA) P50440 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9D964 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9D964 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q9D964 (/ISO)
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