CATH Superfamily 3.70.10.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 17: DNA damage checkpoint control protein RAD17
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
7 | P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA damage checkpoint GO:0000077
A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
|
7 | P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) |
|
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
|
7 | P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) |
|
Reciprocal meiotic recombination GO:0007131
The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
|
7 | P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) P48581 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) P48581 (/IPI) |
|
Checkpoint clamp complex GO:0030896
Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.
|
7 | P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) P48581 (/IDA) |
