The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PPM-type phosphatase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: protein phosphatase 1B isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
18 O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(8 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
18 O75688 (/IPI) O75688 (/IPI) O75688 (/IPI) P20650 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI)
(8 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
17 O75688 (/TAS) O75688 (/TAS) O75688 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS)
(7 more)
Calmodulin-dependent protein phosphatase activity GO:0033192
Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.
14 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(4 more)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
14 P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI) P35813 (/IPI)
(4 more)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
5 O62829 (/ISS) O62829 (/ISS) P20650 (/ISS) P35814 (/ISS) P49443 (/ISS)
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
3 O62829 (/ISS) O62829 (/ISS) P35814 (/ISS)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
1 P49443 (/IDA)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
1 Q9VBF9 (/ISS)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P20650 (/IPI)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P49443 (/ISO)
Calmodulin-dependent protein phosphatase activity GO:0033192
Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.
1 P49443 (/ISO)
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
1 P20650 (/IDA)
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
1 P49443 (/ISO)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
1 P49443 (/ISO)

There are 59 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
N-terminal protein myristoylation GO:0006499
The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
23 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P20650 (/ISS) P35813 (/ISS) P35813 (/ISS) P35813 (/ISS)
(13 more)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
22 C9JIR6 (/IMP) C9JIR6 (/IMP) O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP)
(12 more)
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
17 O75688 (/IDA) O75688 (/IDA) O75688 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(7 more)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
17 O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP)
(7 more)
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
17 O75688 (/IMP) O75688 (/IMP) O75688 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP) P35813 (/IMP)
(7 more)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
15 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(5 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
14 P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS)
(4 more)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
14 P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS)
(4 more)
Negative regulation of SMAD protein complex assembly GO:0010991
Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
14 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(4 more)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
14 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(4 more)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
14 P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP) P35813 (/HMP)
(4 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
14 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(4 more)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
14 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(4 more)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
9 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) P20650 (/ISS) P35814 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) P49443 (/ISS)
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
9 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) P20650 (/ISS) P35814 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS) P49443 (/ISS)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
7 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) P20650 (/ISS) P35814 (/ISS) P35815 (/ISS) Q9VBF9 (/ISS)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Response to UV-C GO:0010225
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
4 O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS)
Negative regulation of stress-activated MAPK cascade GO:0032873
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
4 O62830 (/ISS) P35815 (/ISS) P36993 (/ISS) P36993 (/ISS)
Negative regulation of stress-activated protein kinase signaling cascade GO:0070303
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Negative regulation of stress-activated protein kinase signaling cascade GO:0070303
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
4 A0A0B4K7Q3 (/HGI) Q8IMK7 (/HGI) Q961C5 (/HGI) Q9VAK1 (/HGI)
Regulation of p38MAPK cascade GO:1900744
Any process that modulates the frequency, rate or extent of p38MAPK cascade.
4 A0A0B4K7Q3 (/IGI) Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI)
Response to paraquat GO:1901562
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
4 A0A0B4K7Q3 (/IMP) Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
3 O75688 (/TAS) O75688 (/TAS) O75688 (/TAS)
N-terminal protein myristoylation GO:0006499
The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
3 P36993 (/IDA) P36993 (/IDA) P49443 (/IDA)
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
3 O75688 (/IMP) O75688 (/IMP) O75688 (/IMP)
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
3 O62829 (/ISS) O62829 (/ISS) P35814 (/ISS)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
3 Q8IMK7 (/HGI) Q961C5 (/HGI) Q9VAK1 (/HGI)
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
3 O75688 (/IMP) O75688 (/IMP) O75688 (/IMP)
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
2 A7YYD2 (/IMP) Q5U386 (/IMP)
Negative regulation of interferon-beta production GO:0032688
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
2 P36993 (/ISO) P36993 (/ISO)
Negative regulation of defense response to virus GO:0050687
Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
2 P36993 (/ISO) P36993 (/ISO)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
1 P49443 (/IDA)
Negative regulation of SMAD protein complex assembly GO:0010991
Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
1 P49443 (/ISO)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
1 P49443 (/ISO)
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
1 P49443 (/ISO)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
1 P49443 (/IMP)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
1 Q961C5 (/IMP)
Negative regulation of R7 cell differentiation GO:0045677
Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.
1 Q8IMK7 (/IGI)
Negative regulation of sevenless signaling pathway GO:0045873
Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.
1 Q961C5 (/IGI)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P49443 (/ISO)
Negative regulation of photoreceptor cell differentiation GO:0046533
Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
1 Q961C5 (/IGI)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
1 Q961C5 (/IMP)
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
1 P49443 (/IMP)
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
1 P49443 (/IDA)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 P49443 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
34 A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA)
(24 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
28 A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA) A0A024R6A5 (/IDA)
(18 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
23 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P20650 (/ISS) P35813 (/ISS) P35813 (/ISS) P35813 (/ISS)
(13 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
23 O62829 (/ISS) O62829 (/ISS) O62830 (/ISS) O75688 (/ISS) O75688 (/ISS) O75688 (/ISS) P20650 (/ISS) P35813 (/ISS) P35813 (/ISS) P35813 (/ISS)
(13 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 O75688 (/TAS) O75688 (/TAS) O75688 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS)
(7 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
15 P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA) P35813 (/IDA)
(5 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
14 P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS) P35813 (/TAS)
(4 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
3 O75688 (/IDA) O75688 (/IDA) O75688 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P36993 (/ISO) P36993 (/ISO) P49443 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 P36993 (/IDA) P36993 (/IDA) P49443 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 P36993 (/ISO) P36993 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P49443 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VBF9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9VBF9 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P49443 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P20650 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P49443 (/ISO)
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