The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".
FunFam 45: Hydroxyacylglutathione hydrolase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Hydroxyacylglutathione hydrolase activity GO:0004416
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
|
14 |
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
(4 more) |
|
Hydroxyacylglutathione hydrolase activity GO:0004416
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
|
14 |
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
(4 more) |
|
Hydroxyacylglutathione hydrolase activity GO:0004416
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
|
14 |
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
(4 more) |
|
Hydroxyacylglutathione hydrolase activity GO:0004416
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
|
2 | O94250 (/ISO) Q9UT36 (/ISO) |
|
Hydroxyacylglutathione hydrolase activity GO:0004416
Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
|
1 | Q54MR1 (/ISS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
14 |
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q05584 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
Q12320 (/IDA)
(4 more) |
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
14 |
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q05584 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
Q12320 (/IGI)
(4 more) |
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
14 |
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q05584 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
Q12320 (/IMP)
(4 more) |
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
2 | O94250 (/ISO) Q9UT36 (/ISO) |
|
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione GO:0019243
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
|
1 | Q54MR1 (/ISS) |
|
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
1 | O94250 (/IC) |
|
Cellular detoxification GO:1990748
Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
1 | Q9UT36 (/NAS) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
8 | Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) Q12320 (/HDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
8 | Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) Q12320 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | Q05584 (/IDA) Q05584 (/IDA) Q05584 (/IDA) Q05584 (/IDA) Q05584 (/IDA) Q05584 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O94250 (/HDA) Q9UT36 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O94250 (/HDA) Q9UT36 (/HDA) |
