The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: probable hydrolase PNKD isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q69ZP3 (/IPI) Q8N490 (/IPI) Q8N490 (/IPI) Q8N490 (/IPI) Q8N490 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
4 Q8N490 (/IMP) Q8N490 (/IMP) Q8N490 (/IMP) Q8N490 (/IMP)
Regulation of synaptic transmission, dopaminergic GO:0032225
Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
1 Q69ZP3 (/IMP)
Regulation of dopamine metabolic process GO:0042053
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
1 Q69ZP3 (/IMP)
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
1 Q69ZP3 (/IGI)
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
1 Q69ZP3 (/ISO)
Neuromuscular process controlling posture GO:0050884
Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
1 Q69ZP3 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 A0A024R415 (/IDA) A0A024R415 (/IDA) A0A024R415 (/IDA) A0A024R415 (/IDA) Q8N490 (/IDA) Q8N490 (/IDA) Q8N490 (/IDA) Q8N490 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 Q8N490 (/IDA) Q8N490 (/IDA) Q8N490 (/IDA) Q8N490 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q69ZP3 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q69ZP3 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q69ZP3 (/ISO)
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