The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Clavaminate synthase-like
".
FunFam 1: Trimethyllysine dioxygenase, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Gamma-butyrobetaine dioxygenase activity GO:0008336
Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
|
10 | O75936 (/ISS) O75936 (/ISS) O75936 (/ISS) O75936 (/ISS) Q5R5D8 (/ISS) Q7K4A8 (/ISS) Q924Y0 (/ISS) Q9QZU7 (/ISS) Q9VY24 (/ISS) Q9W5B5 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O75936 (/IPI) O75936 (/IPI) O75936 (/IPI) O75936 (/IPI) Q9NVH6 (/IPI) Q9NVH6 (/IPI) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
4 | O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) |
|
Gamma-butyrobetaine dioxygenase activity GO:0008336
Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
|
4 | O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
4 | O75936 (/IPI) O75936 (/IPI) O75936 (/IPI) O75936 (/IPI) |
|
Trimethyllysine dioxygenase activity GO:0050353
Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.
|
4 | Q0VC74 (/ISS) Q0VC74 (/ISS) Q5F4B3 (/ISS) Q91ZE0 (/ISS) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | Q5R5D8 (/ISS) Q924Y0 (/ISS) Q9QZU7 (/ISS) |
|
Trimethyllysine dioxygenase activity GO:0050353
Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.
|
3 | A0A1D8PNJ2 (/IMP) Q9NVH6 (/IMP) Q9NVH6 (/IMP) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q924Y0 (/ISO) |
|
Gamma-butyrobetaine dioxygenase activity GO:0008336
Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
|
1 | Q9QZU7 (/IMP) |
|
Gamma-butyrobetaine dioxygenase activity GO:0008336
Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
|
1 | Q924Y0 (/ISO) |
|
Gamma-butyrobetaine dioxygenase activity GO:0008336
Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
|
1 | Q9QZU7 (/TAS) |
|
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
|
1 | Q91ZE0 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q924Y0 (/ISO) |
|
Trimethyllysine dioxygenase activity GO:0050353
Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.
|
1 | Q91ZW6 (/IDA) |
|
Trimethyllysine dioxygenase activity GO:0050353
Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.
|
1 | Q91ZE0 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
8 | O75936 (/TAS) O75936 (/TAS) O75936 (/TAS) O75936 (/TAS) Q91ZW6 (/TAS) Q9NVH6 (/TAS) Q9NVH6 (/TAS) Q9QZU7 (/TAS) |
|
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
7 | Q0VC74 (/ISS) Q0VC74 (/ISS) Q5F4B3 (/ISS) Q5R5D8 (/ISS) Q91ZW6 (/ISS) Q924Y0 (/ISS) Q9QZU7 (/ISS) |
|
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
5 | O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) O75936 (/IDA) Q91ZE0 (/IDA) |
|
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
3 | A0A1D8PNJ2 (/IMP) Q9NVH6 (/IMP) Q9NVH6 (/IMP) |
|
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
2 | Q91ZE0 (/ISO) Q924Y0 (/ISO) |
|
Negative regulation of oxidoreductase activity GO:0051354
Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
|
1 | Q91ZE0 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | Q91ZE0 (/IDA) Q91ZW6 (/IDA) Q9NVH6 (/IDA) Q9NVH6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O75936 (/TAS) O75936 (/TAS) O75936 (/TAS) O75936 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | O75936 (/HDA) O75936 (/HDA) O75936 (/HDA) O75936 (/HDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | Q9NVH6 (/TAS) Q9NVH6 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q924Y0 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q91ZE0 (/ISO) |