The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Carbon-nitrogen hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: nitrilase homolog 1 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810
Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
2 O76463 (/TAS) O76464 (/TAS)
Bis(5'-adenosyl)-triphosphatase activity GO:0047710
Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+).
2 O76463 (/IDA) O76464 (/IDA)
Nitrilase activity GO:0000257
Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.
1 Q86X76 (/TAS)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
1 Q8VDK1 (/IDA)
Deaminated glutathione amidase activity GO:0110050
Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine
1 Q94JV5 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
2 O76463 (/IDA) O76464 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q94JV5 (/IEP)
Metabolite repair GO:0110051
A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
1 Q94JV5 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q8VDK1 (/IDA) Q94JV5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q86X76 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8VDK1 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8VDK1 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q94JV5 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
1 Q94JV5 (/IDA)
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