The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Endonuclease/exonuclease/phosphatase
".
FunFam 35: Deoxyribonuclease
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P00639 (/IPI) P00639 (/IPI) P24855 (/IPI) |
|
Deoxyribonuclease I activity GO:0004530
Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
|
2 | P49183 (/IMP) P49183 (/IMP) |
|
Deoxyribonuclease I activity GO:0004530
Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
|
2 | P49183 (/ISO) P49183 (/ISO) |
|
Deoxyribonuclease activity GO:0004536
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
|
2 | P49183 (/ISO) P49183 (/ISO) |
|
Deoxyribonuclease I activity GO:0004530
Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
|
1 | P21704 (/IDA) |
|
Deoxyribonuclease activity GO:0004536
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
|
1 | P21704 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA catabolic process, endonucleolytic GO:0000737
The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
|
10 | O18998 (/ISS) O42446 (/ISS) P00639 (/ISS) P00639 (/ISS) P11936 (/ISS) P11937 (/ISS) P21704 (/ISS) P24855 (/ISS) Q4AEE3 (/ISS) Q767J3 (/ISS) |
|
Neutrophil activation involved in immune response GO:0002283
The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
|
10 | O18998 (/ISS) O42446 (/ISS) P00639 (/ISS) P00639 (/ISS) P11936 (/ISS) P11937 (/ISS) P21704 (/ISS) P24855 (/ISS) Q4AEE3 (/ISS) Q767J3 (/ISS) |
|
Regulation of acute inflammatory response GO:0002673
Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
|
10 | O18998 (/ISS) O42446 (/ISS) P00639 (/ISS) P00639 (/ISS) P11936 (/ISS) P11937 (/ISS) P21704 (/ISS) P24855 (/ISS) Q4AEE3 (/ISS) Q767J3 (/ISS) |
|
Regulation of neutrophil mediated cytotoxicity GO:0070948
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.
|
10 | O18998 (/ISS) O42446 (/ISS) P00639 (/ISS) P00639 (/ISS) P11936 (/ISS) P11937 (/ISS) P21704 (/ISS) P24855 (/ISS) Q4AEE3 (/ISS) Q767J3 (/ISS) |
|
DNA catabolic process, endonucleolytic GO:0000737
The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
|
2 | P49183 (/IDA) P49183 (/IDA) |
|
Neutrophil activation involved in immune response GO:0002283
The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
|
2 | P49183 (/IDA) P49183 (/IDA) |
|
Regulation of acute inflammatory response GO:0002673
Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
|
2 | P49183 (/IDA) P49183 (/IDA) |
|
Regulation of neutrophil mediated cytotoxicity GO:0070948
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.
|
2 | P49183 (/IDA) P49183 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P24855 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P24855 (/HDA) |
