The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 99: Flavin-containing monooxygenase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aliphatic glucosinolate S-oxygenase. [EC: 1.14.13.237]
An omega-(methylthio)alkyl-glucosinolate + NADPH + O(2) = an omega- (methylsulfinyl)alkyl-glucosinolate + NADP(+) + H(2)O.
  • The enzyme is a member of the flavin-dependent monooxygenase (FMO) family (cf. EC 1.14.13.8).
  • The plant Arabidopsis thaliana contains five isoforms.
  • GS-OX1 through GS-OX4 are able to catalyze the S-oxygenation independent of chain length, while GS-OX5 is specific for 8-(methylsulfanyl)octyl glucosinolate.
8 A0A178WQ06 A0A178WQ06 A8MRX0 A8MRX0 Q93Y23 Q94K43 Q9SS04 Q9SXE1
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