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CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 713: FAD-dependent urate hydroxylase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
FAD-dependent urate hydroxylase. [EC: 1.14.13.113]
Urate + NADH + O(2) = 5-hydroxyisourate + NAD(+) + H(2)O.
  • The reaction is part of the purine catabolic pathway in the bacterium Klebsiella pneumoniae.
  • The enzyme is different from EC 1.7.3.3, found in most plants, which produces hydrogen peroxide.
  • The product of the enzyme is a substrate for EC 3.5.2.17.
 9 A0A0H2X4F8 A0A0H2X4F8 A0A0H2X4F8 A0A3E1KVA5 A0A3E1KVA5 A0A3E1KVA5 Q8PDQ6 Q8PDQ6 Q8PDQ6
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