The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 7: Alkyl hydroperoxide reductase, F subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thioredoxin-disulfide reductase activity GO:0004791
Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide.
|
88 |
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
(78 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
88 |
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
P0A9P4 (/IPI)
(78 more) |
|
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
88 |
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
(78 more) |
|
Alkyl hydroperoxide reductase activity GO:0008785
Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.
|
57 |
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
P35340 (/IGI)
(47 more) |
|
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
57 |
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
(47 more) |
|
Alkyl hydroperoxide reductase activity GO:0008785
Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.
|
22 |
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
A0A0F7RI47 (/ISS)
(12 more) |
|
Thioredoxin-disulfide reductase activity GO:0004791
Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide.
|
6 | Q9KSS4 (/ISS) Q9KSS4 (/ISS) Q9KSS4 (/ISS) Q9KSS4 (/ISS) Q9KSS4 (/ISS) Q9KSS4 (/ISS) |
|
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
6 | P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
6 | P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
6 | P9WHH1 (/IEP) P9WHH1 (/IEP) P9WHH1 (/IEP) P9WHH1 (/IEP) P9WHH1 (/IEP) P9WHH1 (/IEP) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
6 | P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) P9WHH1 (/IDA) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
6 | P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
139 |
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
P0A9P4 (/IDA)
(129 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
57 |
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
P35340 (/HDA)
(47 more) |
|
Alkyl hydroperoxide reductase complex GO:0009321
An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.
|
57 |
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
P35340 (/IDA)
(47 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) P9WHH1 (/TAS) |