The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 259: Dihydrolipoamide dehydrogenase, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
4 Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
4 Q02733 (/ISS) Q02733 (/ISS) Q02733 (/ISS) Q02733 (/ISS)
Oxidoreductase activity, acting on NAD(P)H GO:0016651
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
4 Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA)
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
2 Q57YU0 (/ISM) Q57YU0 (/ISM)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic recombination GO:0006312
The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles.
4 Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP)
Microtubule nucleation GO:0007020
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
4 Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA)
Microtubule anchoring GO:0034453
Any process in which a microtubule is maintained in a specific location in a cell.
4 Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP)
Meiotic sister chromatid segregation GO:0045144
The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.
4 Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
4 Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP)
Attachment of mitotic spindle microtubules to kinetochore GO:0051315
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
4 Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP) Q02733 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 Q580K3 (/IDA) Q580K3 (/IDA) Q584K1 (/IDA) Q584K1 (/IDA) Q584K1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q02733 (/HDA) Q02733 (/HDA) Q02733 (/HDA) Q02733 (/HDA)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
4 Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA) Q02733 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q57YU0 (/IDA) Q57YU0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q57YU0 (/ISM) Q57YU0 (/ISM)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q57YU0 (/RCA) Q57YU0 (/RCA)
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