The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 23: Dimethylaniline monooxygenase [N-oxide-forming]
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
N,N-dimethylaniline monooxygenase activity GO:0004499
Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
|
2 | Q99518 (/IDA) Q9EQ76 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P31513 (/IPI) P31513 (/IPI) |
|
Lactoylglutathione lyase activity GO:0004462
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
|
1 | Q6DF15 (/ISS) |
|
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
|
1 | Q8K4B7 (/NAS) |
|
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
|
1 | Q9EQ76 (/TAS) |
|
N,N-dimethylaniline monooxygenase activity GO:0004499
Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
|
1 | P31512 (/NAS) |
|
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
|
1 | Q9EQ76 (/IPI) |
|
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
1 | Q9EQ76 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
NADPH oxidation GO:0070995
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
|
8 | P17635 (/ISS) Q28505 (/ISS) Q5REK0 (/ISS) Q6IRI9 (/ISS) Q8HZ69 (/ISS) Q8HZ70 (/ISS) Q8HZ70 (/ISS) Q8HZ70 (/ISS) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
3 | P31513 (/TAS) P31513 (/TAS) Q99518 (/TAS) |
|
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
|
2 | Q99518 (/IDA) Q9EQ76 (/IDA) |
|
NADPH oxidation GO:0070995
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
|
2 | P36367 (/IDA) Q99518 (/IDA) |
|
Organic acid metabolic process GO:0006082
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
|
1 | Q99518 (/IDA) |
|
NADP metabolic process GO:0006739
The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
|
1 | Q99518 (/IDA) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
1 | Q99518 (/IDA) |
|
Toxin metabolic process GO:0009404
The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | Q99518 (/IDA) |
|
Drug catabolic process GO:0042737
The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q8VHG0 (/IMP) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q6DF15 (/ISS) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
8 | P17635 (/ISS) Q28505 (/ISS) Q5REK0 (/ISS) Q6IRI9 (/ISS) Q8HZ69 (/ISS) Q8HZ70 (/ISS) Q8HZ70 (/ISS) Q8HZ70 (/ISS) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | A0A024QYY6 (/IDA) A0A024QYY6 (/IDA) P49326 (/IDA) P49326 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0A024QYY6 (/IDA) A0A024QYY6 (/IDA) P49326 (/IDA) P49326 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
3 | P31513 (/TAS) P31513 (/TAS) Q99518 (/TAS) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
2 | P31513 (/TAS) P31513 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | G5EBJ9 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q99518 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9EQ76 (/IDA) |
