View in Gene3D

CATH Superfamily 3.50.50.60

FAD/NAD(P)-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 229: NADPH:adrenodoxin oxidoreductase, mitochondrial

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ferredoxin--NADP(+) reductase. [EC: 1.18.1.2]
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
  • In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin.
  • Formerly EC 1.6.7.1 and EC 1.6.99.4.
 64 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0E8V1W9 A0A0H3M2M5 A0A0H3M2M5
(54 more...)
Adrenodoxin-NADP(+) reductase. [EC: 1.18.1.6]
2 reduced adrenodoxin + NADP(+) = 2 oxidized adrenodoxin + NADPH.
  • The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component in the mitochondrial cytochrome P450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones.
 5 C4IY01 C4IY01 Q54KG7 Q9V3T9 Q9V3T9
CATH-Gene3D is a Global Biodata Core Resource Learn more...