The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 178: All-trans-retinol 13,14-reductase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
All-trans-retinol 13,14-reductase. [EC: 1.3.99.23]
All-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced acceptor.
  • The reaction is only known to occur in the opposite direction to that given above, with the enzyme being specific for all-trans-retinol as substrate.
  • Neither all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol isomers are substrates.
  • May play a role in the metabolism of vitamin A.
4 Q64FG0 Q64FW2 Q6NUM9 Q8VHE9
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