The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Glycerol-3-phosphate dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycerol-3-phosphate dehydrogenase (quinone) activity GO:0004368
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
10 P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) Q4Q8P6 (/IDA) Q9SS48 (/IDA) Q9SS48 (/IDA)
Glycerol-3-phosphate dehydrogenase (quinone) activity GO:0004368
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
8 P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) Q7K569 (/IMP)
Glycerol-3-phosphate dehydrogenase (quinone) activity GO:0004368
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
5 P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
5 P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
3 Q384S7 (/IDA) Q384S7 (/IDA) Q4Q8P6 (/IDA)
Glycerol-3-phosphate dehydrogenase (quinone) activity GO:0004368
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
2 Q384S7 (/ISO) Q384S7 (/ISO)
Glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367
Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
1 P35571 (/IDA)
Glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367
Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
1 Q64521 (/ISO)
Glycerol-3-phosphate dehydrogenase (quinone) activity GO:0004368
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
1 C8VRM5 (/RCA)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Replicative cell aging GO:0001302
The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.
7 P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
7 P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP)
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
7 P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA)
Glycerophosphate shuttle GO:0006127
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
7 P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) Q9SS48 (/TAS) Q9SS48 (/TAS)
Glycerophosphate shuttle GO:0006127
The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
3 Q7K569 (/IMP) Q9SS48 (/IMP) Q9SS48 (/IMP)
Glycerol catabolic process GO:0019563
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
3 Q384S7 (/RCA) Q384S7 (/RCA) Q4Q8P6 (/RCA)
Glycerol catabolic process GO:0019563
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
2 Q9SS48 (/IMP) Q9SS48 (/IMP)
Glycerol catabolic process GO:0019563
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
2 Q9SS48 (/TAS) Q9SS48 (/TAS)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
1 Q7K569 (/ISS)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
1 C8VRM5 (/RCA)
Glycerol-3-phosphate metabolic process GO:0006072
The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
1 P35571 (/IDA)
Glycerol-3-phosphate metabolic process GO:0006072
The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
1 Q64521 (/IMP)
Glycerol-3-phosphate metabolic process GO:0006072
The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
1 Q64521 (/ISO)
Glycerol-3-phosphate metabolic process GO:0006072
The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
1 O14400 (/ISS)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 Q64521 (/IMP)
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
1 O14400 (/ISO)
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
1 P35571 (/IDA)
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
1 Q64521 (/ISO)
Flight behavior GO:0007629
The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
1 Q7K569 (/IMP)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q64521 (/IGI)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
1 Q64521 (/IGI)
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
1 C8VRM5 (/IEP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 O14400 (/HDA) P32191 (/HDA) P32191 (/HDA) P32191 (/HDA) P32191 (/HDA) P32191 (/HDA) P32191 (/HDA) P32191 (/HDA) Q64521 (/HDA) Q7K569 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) Q9SS48 (/IDA) Q9SS48 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
7 P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP) P32191 (/IMP)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
7 P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA) P32191 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
5 P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS) P43304 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q384S7 (/EXP) Q384S7 (/EXP) Q4Q8P6 (/EXP)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q384S7 (/RCA) Q384S7 (/RCA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q7K569 (/IC)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q7K569 (/ISS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q64521 (/HDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q7K569 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 A0A1D8PMP1 (/IDA)
Glycerol-3-phosphate dehydrogenase complex GO:0009331
An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.
1 O14400 (/ISO)
Glycerol-3-phosphate dehydrogenase complex GO:0009331
An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.
1 Q64521 (/TAS)
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