The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 129: Kynurenine 3-monooxygenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Kynurenine 3-monooxygenase activity GO:0004502
Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
Kynurenine 3-monooxygenase activity GO:0004502
Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
|
6 | P38169 (/IMP) P38169 (/IMP) P38169 (/IMP) P38169 (/IMP) P38169 (/IMP) P38169 (/IMP) |
|
NAD(P)H oxidase activity GO:0016174
Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
Kynurenine 3-monooxygenase activity GO:0004502
Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
|
3 | A8Y432 (/ISS) Q21795 (/ISS) Q54RE8 (/ISS) |
|
Kynurenine 3-monooxygenase activity GO:0004502
Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
|
1 | Q5A7M3 (/ISA) |
|
Kynurenine 3-monooxygenase activity GO:0004502
Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
|
1 | Q5B2N0 (/RCA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
NAD metabolic process GO:0019674
The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
'de novo' NAD biosynthetic process from tryptophan GO:0034354
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
6 | P38169 (/IGI) P38169 (/IGI) P38169 (/IGI) P38169 (/IGI) P38169 (/IGI) P38169 (/IGI) |
|
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
|
6 | P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) P38169 (/IDA) |
|
NAD metabolic process GO:0019674
The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
|
3 | A8Y432 (/ISS) Q21795 (/ISS) Q54RE8 (/ISS) |
|
Aromatic amino acid family biosynthetic process GO:0009073
The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
|
1 | Q5B2N0 (/RCA) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q5A7M3 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5A7M3 (/IMP) |
|
'de novo' NAD biosynthetic process from tryptophan GO:0034354
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
1 | Q5A7M3 (/ISA) |
|
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
|
1 | Q5A7M3 (/IMP) |
|
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
|
1 | Q5A7M3 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
6 | P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) P38169 (/HDA) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
3 | A8Y432 (/ISS) Q21795 (/ISS) Q54RE8 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q5A7M3 (/IDA) |
