The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 116: Glycine oxidase ThiO

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine oxidase activity GO:0043799
Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.
15 O31616 (/IDA) O31616 (/IDA) O31616 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA)
(5 more)
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
15 O31616 (/IDA) O31616 (/IDA) O31616 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 A0A0H2UQX6 (/IPI) A0A0H2UQX6 (/IPI)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2 Q81PT2 (/ISS) Q81PT2 (/ISS)
Oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor GO:0016647
Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.
2 A0A0F7RN07 (/ISS) A0A0F7RN07 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
15 O31616 (/IDA) O31616 (/IDA) O31616 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA)
(5 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
10 Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA) Q5L2C2 (/IDA)
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
3 O31616 (/IMP) O31616 (/IMP) O31616 (/IMP)
Glycine catabolic process GO:0006546
The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
2 A0A0F7RN07 (/ISS) A0A0F7RN07 (/ISS)
Thiamine biosynthetic process GO:0009228
The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
2 Q88Q83 (/NAS) Q88Q83 (/NAS)
Retrograde transport, endosome to Golgi GO:0042147
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
1 Q10058 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
1 Q10058 (/ISO)
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