The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 113: NADPH-dependent 2,4-dienoyl-CoA reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
21 |
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
P42593 (/IPI)
(11 more) |
2,4-dienoyl-CoA reductase (NADPH) activity GO:0008670
Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.
|
21 |
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
(11 more) |
2,4-dienoyl-CoA reductase (NADPH) activity GO:0008670
Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.
|
21 |
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
(11 more) |
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
21 |
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
(11 more) |
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
21 |
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
(11 more) |
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
|
21 |
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
P42593 (/IDA)
(11 more) |
2,4-dienoyl-CoA reductase (NADPH) activity GO:0008670
Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.
|
14 |
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q5LMH7 (/ISS)
Q87YJ3 (/ISS)
Q8EEG3 (/ISS)
Q9KQK5 (/ISS)
(4 more) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway GO:0033543
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
21 |
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
P42593 (/IMP)
(11 more) |
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
13 |
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q48L13 (/ISS)
Q5LMH7 (/ISS)
Q87YJ3 (/ISS)
Q9KQK5 (/ISS)
Q9KQK5 (/ISS)
(3 more) |
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
1 | Q8EEG3 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
3 | O50431 (/HDA) O50431 (/HDA) O50431 (/HDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | O50431 (/HDA) O50431 (/HDA) O50431 (/HDA) |