The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 101: lycopene epsilon cyclase, chloroplastic

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Lycopene beta-cyclase. [EC: 5.5.1.19]
Carotenoid psi-end group = carotenoid beta-end group.
  • Lycopene has a psi-end group at both ends.
  • When acting on one end, this enzyme forms gamma-carotene.
  • When acting on both ends it forms beta-carotene.
  • It also acts on neurosporene to give beta-zeacarotene.
  • Formerly EC 5.5.1.n2.
9 A0A178VBX7 A0A178VBX7 A6YS01 A6YS01 K4C9E2 Q38933 Q38933 Q43503 Q43503
Capsanthin/capsorubin synthase. [EC: 5.3.99.8]
(1) Violaxanthin = capsorubin. (2) Antheraxanthin = capsanthin.
  • Induced during chromoplast differentiation in plants.
  • Isomerization of the epoxide ring of violaxanthin gives the cyclopentyl-ketone of capsorubin or capsanthin.
9 A0A089NBH9 A0A089NBH9 A0A089NBH9 A0A1U8H3A2 A0A1U8H3A2 A0A1U8H3A2 Q42435 Q42435 Q42435
Lycopene epsilon-cyclase. [EC: 5.5.1.18]
Carotenoid psi-end group = carotenoid epsilon-end group.
  • The carotenoid lycopene has the psi-end group at both ends.
  • When acting on one end, this enzyme forms delta-carotene.
  • When acting on both ends, it forms epsilon-carotene.
2 O65837 Q38932
Neoxanthin synthase. [EC: 5.3.99.9]
Violaxanthin = neoxanthin.
  • The opening of the epoxide ring of violaxanthin generates a chiral allene.
  • Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants.
2 K4C9E2 Q9M424
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