CATH Superfamily 3.50.30.30
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: N-acetylated-alpha-linked acidic dipeptidase 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Carboxypeptidase activity GO:0004180
Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
|
3 | O35409 (/IDA) Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
3 | O35409 (/IDA) Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
N-formylglutamate deformylase activity GO:0050129
Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.
|
2 | Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
Carboxypeptidase activity GO:0004180
Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
|
1 | Q9Y3Q0 (/NAS) |
|
Metallocarboxypeptidase activity GO:0004181
Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
1 | Q04609 (/IDA) |
|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
1 | Q04609 (/NAS) |
|
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | Q9Y3Q0 (/NAS) |
|
Dipeptidyl-peptidase activity GO:0008239
Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.
|
1 | Q9Y3Q0 (/NAS) |
|
Dipeptidase activity GO:0016805
Catalysis of the hydrolysis of a dipeptide.
|
1 | O35409 (/IDA) |
|
Dipeptidase activity GO:0016805
Catalysis of the hydrolysis of a dipeptide.
|
1 | Q9Y3Q0 (/NAS) |
|
Ac-Asp-Glu binding GO:1904492
Interacting selectively and non-covalently with Ac-Asp-Glu.
|
1 | Q04609 (/IDA) |
|
Tetrahydrofolyl-poly(glutamate) polymer binding GO:1904493
Interacting selectively and non-covalently with tetrahydrofolyl-poly(glutamate) polymer.
|
1 | Q04609 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
5 | O35409 (/IDA) P70627 (/IDA) Q04609 (/IDA) Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
2 | Q04609 (/NAS) Q9Y3Q0 (/NAS) |
|
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
|
2 | Q04609 (/TAS) Q9Y3Q0 (/TAS) |
|
Neurotransmitter catabolic process GO:0042135
The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
|
2 | Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
1 | O35409 (/ISO) |
|
Folic acid-containing compound metabolic process GO:0006760
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
|
1 | O35409 (/IDA) |
|
C-terminal protein deglutamylation GO:0035609
The removal of a C-terminal, gene-encoded glutamate residue from a protein.
|
1 | Q04609 (/IDA) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | P70627 (/IMP) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | O35409 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O35409 (/IDA) Q9CZR2 (/IDA) Q9CZR2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q04609 (/TAS) Q9Y3Q0 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q04609 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O35409 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q04609 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q04609 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q04609 (/NAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q04609 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9Y3Q0 (/NAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q04609 (/HDA) |
