CATH Superfamily 3.50.30.30
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 19: Signal peptide peptidase like 2A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8TCT8 (/IPI) |
|
Aspartic endopeptidase activity, intramembrane cleaving GO:0042500
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.
|
1 | Q8TCT8 (/IDA) |
|
Aspartic endopeptidase activity, intramembrane cleaving GO:0042500
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.
|
1 | Q9JJF9 (/ISO) |
|
Aspartic endopeptidase activity, intramembrane cleaving GO:0042500
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.
|
1 | Q9JJF9 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q8TCT8 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9JJF9 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9JJF9 (/ISS) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Membrane protein ectodomain proteolysis GO:0006509
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
|
1 | Q8TCT8 (/IDA) |
|
Membrane protein ectodomain proteolysis GO:0006509
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
|
1 | Q9JJF9 (/ISO) |
|
Membrane protein ectodomain proteolysis GO:0006509
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
|
1 | Q9JJF9 (/ISS) |
|
Regulation of tumor necrosis factor-mediated signaling pathway GO:0010803
Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
|
1 | Q8TCT8 (/TAS) |
|
Membrane protein intracellular domain proteolysis GO:0031293
The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
|
1 | Q8TCT8 (/IDA) |
|
Membrane protein intracellular domain proteolysis GO:0031293
The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
|
1 | Q8TCT8 (/IMP) |
|
Membrane protein intracellular domain proteolysis GO:0031293
The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
|
1 | Q9JJF9 (/ISO) |
|
Membrane protein intracellular domain proteolysis GO:0031293
The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
|
1 | Q9JJF9 (/ISS) |
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
1 | Q8TCT8 (/IDA) |
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
1 | Q9JJF9 (/ISO) |
|
Membrane protein proteolysis GO:0033619
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
|
1 | Q9JJF9 (/ISS) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q8TCT8 (/IMP) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q9JJF9 (/ISO) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
1 | Q9JJF9 (/ISS) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q8TCT8 (/HDA) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q9JJF9 (/IDA) |
|
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q8TCT8 (/IDA) |
|
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
1 | Q9JJF9 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8TCT8 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9JJF9 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8TCT8 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q8TCT8 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9JJF9 (/ISO) |
|
Golgi-associated vesicle membrane GO:0030660
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
|
1 | Q8TCT8 (/IDA) |
|
Golgi-associated vesicle membrane GO:0030660
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
|
1 | Q9JJF9 (/ISO) |
|
Golgi-associated vesicle membrane GO:0030660
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
|
1 | Q9JJF9 (/ISS) |
|
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
|
1 | Q9JJF9 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q8TCT8 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9JJF9 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q8TCT8 (/HDA) |
|
Integral component of cytoplasmic side of endoplasmic reticulum membrane GO:0071458
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.
|
1 | Q8TCT8 (/IDA) |
|
Integral component of cytoplasmic side of endoplasmic reticulum membrane GO:0071458
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.
|
1 | Q9JJF9 (/ISO) |
|
Integral component of cytoplasmic side of endoplasmic reticulum membrane GO:0071458
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.
|
1 | Q9JJF9 (/ISS) |
|
Integral component of lumenal side of endoplasmic reticulum membrane GO:0071556
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.
|
1 | Q8TCT8 (/IDA) |
|
Integral component of lumenal side of endoplasmic reticulum membrane GO:0071556
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.
|
1 | Q9JJF9 (/ISO) |
|
Integral component of lumenal side of endoplasmic reticulum membrane GO:0071556
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.
|
1 | Q9JJF9 (/ISS) |
