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CATH Superfamily 3.50.20.20

Janus/Ocnus

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Janus/Ocnus
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 14 kDa phosphohistidine phosphatase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphohistidine phosphatase. [EC: 3.9.1.3]
A [protein]-N-phospho-L-histidine + H(2)O = a [protein]-L-histidine + phosphate.
  • This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides.
  • The enzyme acts on phosphate groups attached to both the pros- and tele-nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most).
  • The substrate specificity depends on the amino acid sequence or structural context of the phosphohistidine in a phosphoprotein.
  • The enzyme is also active on free phosphoramidate and peptide-bound phospholysine.
 9 P59083 P83468 Q32PA4 Q5R8L6 Q9DAK9 Q9NRX4 Q9NRX4 V9HWC4 V9HWC4