The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Kinesin motor domain
".
FunFam 24: Myosin heavy chain, isoform J
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | A7E2Y1 (/IPI) P02566 (/IPI) |
|
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
|
2 | P02566 (/IDA) P02567 (/IDA) |
|
Microfilament motor activity GO:0000146
Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
1 | P02566 (/IDA) |
|
Microfilament motor activity GO:0000146
Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
1 | P12845 (/ISS) |
|
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
|
1 | P12844 (/IMP) |
|
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
|
1 | Q60LV4 (/ISS) |
|
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
|
1 | P05661 (/IMP) |
|
Actin-dependent ATPase activity GO:0030898
Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate.
|
1 | P05661 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P05661 (/IDA) |
|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | P02566 (/IDA) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
3 | P02566 (/IMP) P02567 (/IMP) P05661 (/IMP) |
|
Skeletal muscle myosin thick filament assembly GO:0030241
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.
|
2 | P02566 (/IMP) P05661 (/IMP) |
|
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
|
2 | P02566 (/IMP) P05661 (/IMP) |
|
Muscle cell development GO:0055001
The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.
|
2 | E7FD18 (/IMP) R4GDZ5 (/IMP) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
1 | Q1JPZ0 (/IMP) |
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
1 | P12845 (/ISS) |
|
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
|
1 | P05661 (/IMP) |
|
Epithelial cell migration, open tracheal system GO:0007427
The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
|
1 | P05661 (/IMP) |
|
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
1 | P05661 (/IMP) |
|
Adult somatic muscle development GO:0007527
The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.
|
1 | P05661 (/IMP) |
|
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | P12844 (/IMP) |
|
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q60LV4 (/ISS) |
|
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
|
1 | Q1JPZ0 (/IDA) |
|
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
|
1 | P02566 (/IMP) |
|
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
|
1 | P05661 (/IMP) |
|
Myosin filament organization GO:0031033
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.
|
1 | P05661 (/IMP) |
|
Myosin filament assembly GO:0031034
The aggregation, arrangement and bonding together of a filament composed of myosin molecules.
|
1 | G3V6E1 (/TAS) |
|
Muscle cell differentiation GO:0042692
The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
|
1 | P05661 (/IMP) |
|
Pharyngeal pumping GO:0043050
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
|
1 | P02567 (/IMP) |
|
Regulation of myosin II filament assembly GO:0043520
Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.
|
1 | P05661 (/IDA) |
|
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | P05661 (/IMP) |
|
Embryonic skeletal system development GO:0048706
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.
|
1 | Q1JPZ0 (/IMP) |
|
Skeletal muscle fiber development GO:0048741
The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
|
1 | Q1JPZ0 (/IMP) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | P05661 (/IMP) |
|
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
1 | P12844 (/IMP) |
|
Flight GO:0060361
Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
|
1 | P05661 (/IMP) |
|
Muscle thin filament assembly GO:0071689
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
|
1 | P05661 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Striated muscle myosin thick filament GO:0005863
Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.
|
3 | P02566 (/IDA) P02567 (/IDA) P12844 (/IDA) |
|
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
|
3 | P02566 (/IDA) P05661 (/IDA) P12844 (/IDA) |
|
Polytene chromosome puff GO:0005703
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
|
1 | P05661 (/IDA) |
|
Muscle myosin complex GO:0005859
A filament of myosin found in a muscle cell of any type.
|
1 | P02566 (/IDA) |
|
Muscle myosin complex GO:0005859
A filament of myosin found in a muscle cell of any type.
|
1 | P12845 (/ISS) |
|
Striated muscle myosin thick filament GO:0005863
Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.
|
1 | P05661 (/HDA) |
|
Striated muscle myosin thick filament GO:0005863
Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.
|
1 | P12844 (/IMP) |
|
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | P05661 (/IDA) |
|
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
|
1 | Q60LV4 (/ISS) |
|
Cardiac myofibril GO:0097512
A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
1 | A2AQP0 (/IDA) |
