The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ureohydrolase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Arginase 1, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Arginase activity GO:0004053
Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
4 B8AU84 (/IDA) B8AU84 (/IDA) Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Agmatinase activity GO:0008783
Catalysis of the reaction: agmatine + H(2)O = putrescine + urea.
4 P46637 (/IDA) P46637 (/IDA) Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
4 P46637 (/IDA) P46637 (/IDA) Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Arginase activity GO:0004053
Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
2 P46637 (/IGI) P46637 (/IGI)
Arginase activity GO:0004053
Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
2 P46637 (/IMP) P46637 (/IMP)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
2 B8AU84 (/IDA) B8AU84 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Putrescine biosynthetic process from arginine, using agmatinase GO:0033389
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.
4 P46637 (/IDA) P46637 (/IDA) Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
2 B8AU84 (/IDA) B8AU84 (/IDA)
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
2 P46637 (/IGI) P46637 (/IGI)
Proline metabolic process GO:0006560
The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
2 Q9ZPF5 (/IMP) Q9ZPF5 (/IMP)
Tyrosine metabolic process GO:0006570
The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
2 Q9ZPF5 (/IMP) Q9ZPF5 (/IMP)
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
2 Q9ZPF5 (/IMP) Q9ZPF5 (/IMP)
Putrescine metabolic process GO:0009445
The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.
2 Q9ZPF5 (/IMP) Q9ZPF5 (/IMP)
Putrescine biosynthetic process GO:0009446
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
2 Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Putrescine biosynthetic process GO:0009446
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
2 Q9ZPF5 (/IGI) Q9ZPF5 (/IGI)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
2 P46637 (/IEP) P46637 (/IEP)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 Q9ZPF5 (/IMP) Q9ZPF5 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 P46637 (/IDA) P46637 (/IDA) Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q9ZPF5 (/IDA) Q9ZPF5 (/IDA)
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