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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 78: Adenosylmethionine-8-amino-7-oxononanoate aminotra...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosylmethionine--8-amino-7-oxononanoate transaminase. [EC: 2.6.1.62]
S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.
  • S-adenosylhomocysteine can also act as donor.
 55 A0A0D5NCF6 A0A0D5NCF6 A0A0D6HN86 A0A0D6HN86 A0A0D6HN86 A0A0D6HN86 A0A0D6HN86 A0A0D6HN86 A0A0D6HN86 A0A0E1AJS4
(45 more...)
Lysine--8-amino-7-oxononanoate transaminase. [EC: 2.6.1.105]
L-lysine + 8-amino-7-oxononanoate = (S)-2-amino-6-oxohexanoate + 7,8- diaminononanoate.
  • Participates in the pathway for biotin biosynthesis.
  • The enzyme from the bacterium Bacillus subtilis cannot use S-adenosyl-L-methionine as amino donor and catalyzes an alternative reaction for the conversion of 8-amino-7-oxononanoate to 7,8- diaminononanoate (cf. EC 2.6.1.62).
  • Formerly EC 2.6.1.n2.
 16 A0A162RZA9 A0A162RZA9 A0A162RZA9 A0A162RZA9 A0A1B2BE70 A0A1B2BE70 A0A1B2BE70 A0A1B2BE70 L8ANI2 L8ANI2
(6 more...)