View in Gene3D

CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: 5-aminolevulinate synthase, mitochondrial

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glycine C-acetyltransferase. [EC: 2.3.1.29]
Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate.
  • Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.
  • This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex.
 15778 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0 A0A026UXG0
(15768 more...)
8-amino-7-oxononanoate synthase. [EC: 2.3.1.47]
Pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO(2) + holo-[acyl-carrier protein].
  • The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.
  • Pimeloyl-CoA can be used with lower efficiency.
 216 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5NNH9 A0A0B5V7G7 A0A0B5V7G7
(206 more...)
5-aminolevulinate synthase. [EC: 2.3.1.37]
Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).
    		 44 A0A2R9CAD9 A0A2R9CAD9 A0A2R9CAD9 A0A2R9CAD9 A0A2Y9MC53 A0A2Y9MC53 A2AFM0 A2AFM0 A6QLI6 H2QMR0
    (34 more...)
    Serine C-palmitoyltransferase. [EC: 2.3.1.50]
    Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2).
      		 1 Q54EX5
      CATH-Gene3D is a Global Biodata Core Resource Learn more...