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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39: Tryptophanase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 106 P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI)
(96 more)
Tryptophanase activity GO:0009034
Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)
Tryptophanase activity GO:0009034
Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.
 106 P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP)
(96 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)
Potassium ion binding GO:0030955
Interacting selectively and non-covalently with potassium (K+) ions.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 106 P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI) P0A853 (/IPI)
(96 more)
L-cysteine desulfhydrase activity GO:0080146
Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.
 106 P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP)
(96 more)
Tryptophanase activity GO:0009034
Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.
 6 Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
 106 P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP) P0A853 (/IMP)
(96 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
 6 Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS) Q9KN05 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 106 P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA)
(96 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 106 P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA) P0A853 (/HDA)
(96 more)
Cell pole GO:0060187
Either of two different areas at opposite ends of an axis of a cell.
 106 P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA) P0A853 (/IDA)
(96 more)