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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Adenosylmethionine-8-amino-7-oxononanoate aminotra...

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Putrescine--pyruvate transaminase. [EC: 2.6.1.113]
Putrescine + pyruvate = 4-aminobutanal + alanine.
  • The enzyme, studied in the bacterium Pseudomonas aeruginosa, participates in a putrescine degradation pathway.
  • Cf. EC 2.6.1.82.
 121 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3 A0A069Q9J3
(111 more...)
Beta-alanine--pyruvate transaminase. [EC: 2.6.1.18]
L-alanine + 3-oxopropanoate = pyruvate + beta-alanine.
    		 49 A0A069QET9 A0A069QET9 A0A069QET9 A0A069QET9 A0A069QET9 A0A069QET9 A0A069QET9 A0A1F0J551 A0A1F0J551 A0A1F0J551
    (39 more...)
    4-aminobutyrate--pyruvate transaminase. [EC: 2.6.1.96]
    (1) 4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine. (2) 4-aminobutanoate + glyoxylate = succinate semialdehyde + glycine.
    • The enzyme is found in plants that do not have the 2-oxoglutarate dependent enzyme (cf. EC 2.6.1.19).
    • The reaction with pyruvate is reversible while the reaction with glyoxylate only takes place in the forward direction.
    		 16 A0A0E0N8S7 A0A0E0N8S7 B8BBZ7 Q01K11 Q01K12 Q01K12 Q6ZCF0 Q6ZH29 Q6ZH29 Q7XN11
    (6 more...)
    Adenosylmethionine--8-amino-7-oxononanoate transaminase. [EC: 2.6.1.62]
    S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4- methylthio-2-oxobutanoate + 7,8-diaminononanoate.
    • S-adenosylhomocysteine can also act as donor.
    		 13 A0A1W0VM77 A0A1W0VM77 A0A1Y3E1S1 A0A1Y3E1S1 A0A1Y3E1S1 A0A2J9KII0 A0A2J9KII0 A0A2J9KII0 O25627 O25627
    (3 more...)
    Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]
    L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.
    • Differs from EC 2.6.1.46, which has pyruvate as the amino-group acceptor.
    • This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
    		 4 A0A1B8NWM3 A0A1B8NWM3 E1V7V7 E1V7V7
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