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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: 4-aminobutyrate aminotransferase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-aminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.19]
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
  • Some preparations also act on beta-alanine, 5-aminopentanoate and (R,S)-3-amino-2-methylpropanoate.
 859 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37 A0A037YB37
(849 more...)
5-aminovalerate transaminase. [EC: 2.6.1.48]
5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate.
    		 607 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3 A0A069FDF3
    (597 more...)
    (S)-3-amino-2-methylpropionate transaminase. [EC: 2.6.1.22]
    (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3- oxopropanoate + L-glutamate.
    • Also acts on beta-alanine and other omega-amino acids having carbon chains between 2 and 5.
    • The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC 2.6.1.40, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.
    		 148 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3 A0A045JJV3
    (138 more...)